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    Sabatino MAIONE

    Insegnamento di PHARMACOLOGY 1

    Corso di laurea magistrale a ciclo unico in MEDICINA E CHIRURGIA

    SSD: BIO/14

    CFU: 5,00

    ORE PER UNITÀ DIDATTICA: 50,00

    Periodo di Erogazione: Annualità Singola

    English

    Teaching language

    English

    Contents

    knowledge of general rpinciples of pharmacodynamic, pharmacokinetic and drug interaction; knowledge of drugs acting at neurotransmissions
    knowledge of toxicology included drug abuse and treatment of poisoning

    Textbook and course materials

    Book: Rang &Dale’s 8th edition
    Goodmann and Gilmans: The pharmacological basis of therapeutics 11 Edition

    Course objectives

    Correlation of pharmacology with relataed medical sciences emphasizing the apllication of pharmacodynamics and pharmacokinetics to therapeutics

    Prerequisites

    knowledge of biochemistry, physiology, physiopathology

    Teaching methods

    Classroom

    Evaluation methods

    Evaluation of student proficiency is based on oral test (viva voce). The oral exam covers all the aspects of the theory of pharmacology. The questions will be as specific to evaluate the basic knowledge of the topic. The student should be able to discuss on the topic and be able to connect and analyze the different subjects. This means that the student must know the key steps of basic pharmacology, the most relevant for the therapy. Moreover, the student must have a deep knowledge of the most common therapies being able to connect the drugs with diseases. In order to test the acquisition of this ability the student will be asked to solve simple clinical therapeutic oriented problem, e.g recognize a possible drug interaction, the possible adverse reactions and their clinical manifestation. The final grade is expressed in 30/30 were 18 represents the minimum and 30 the maximum and it is established during the oral exam.

    Course Syllabus

    Pharmacodynamic: general principles, molecular aspect, cellular aspect
    Pharmacokinetics: absorption, distribution, metabolism and excretion
    Pharmcokinetic parameters
    Drug interactions
    Chemical mediators and autonomic nervous system: Cholinergic, Noradrenergic, GABAergic, Glutammatergic, Opioid, Cannabinoid, 5-HT and histamine system
    Purines, peptides and nitric oxide
    Principles of toxicology included drug abuse and treatment of poisoning

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